The journey to Enlightenment

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چکیده

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The Long Way to Enlightenment

Electronic cardiac pacemakers are the primary therapy for sinus node dysfunction and high-degree AV block. Although uncommon, infections, lead failures, and vascular complications do result in mortality and morbidity for some patients.1 Battery life limitations require device changes, which contribute to infection risk. In addition, providing adequate rate adaptation to physical activity as wel...

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The Journey of Skiing: Starting from the Altay Region Extending to the Winter Olympic Games

Background. The skiing was first used in the history of mankind for transportation and hunting in the Altay Mountains, where harsh and long winter conditions exist. The use of skiing continued in many cultures and eventually turned into a sport where not the Winter Olympic Games serve as a venue for the competition. Objectives. This review aims to outline the phases of skiing and highlight how...

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The Journey to smORFland

The genome sequences completed so far contain more than 20 000 genes with unknown function and no similarity to genes in other genomes. The origin and evolution of the orphan genes is an enigma. Here, we discuss the suggestion that some orphan genes may represent pseudogenes or short fragments of genes that were functional in the genome of a common ancestor. These may be the remains of unsucces...

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The peripheral axons of vertebrate tactile somatosensory neurons travel long distances from ganglia just outside the central nervous system to the skin. Once in the skin these axons form elaborate terminals whose organization must be regionally patterned to detect and accurately localize different kinds of touch stimuli. This review describes key studies that identified choice points for somato...

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ژورنال

عنوان ژورنال: Nature

سال: 2003

ISSN: 0028-0836,1476-4687

DOI: 10.1038/423482a